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GDP-Mannose Pyrophosphorylase: A Biologically Validated Target for Drug Development Against Leishmaniasis

Leishmaniases are neglected tropical diseases that threaten about 350 million people in 98 countries around the world. In order to find new antileishmanial drugs, an original approach consists in reducing the pathogenic effect of the parasite by impairing the glycoconjugate biosynthesis, necessary f...

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Autori principali: Sébastien Pomel, Wei Mao, Tâp Ha-Duong, Christian Cavé, Philippe M. Loiseau
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019-05-01
Serie:Frontiers in Cellular and Infection Microbiology
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Accesso online:https://www.frontiersin.org/article/10.3389/fcimb.2019.00186/full
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