Clonogenicity-based radioresistance determines the expression of immune suppressive immune checkpoint molecules after hypofractionated irradiation of MDA-MB-231 triple-negative breast cancer cells

Only a subset of patients with triple-negative breast cancer (TNBC) benefits from a combination of radio- (RT) and immunotherapy. Therefore, we aimed to examine the impact of radioresistance and brain metastasizing potential on the immunological phenotype of TNBC cells following hypofractionated RT...

Полное описание

Библиографические подробности

Главные авторы:	Simon Gehre, Felix Meyer, Azzaya Sengedorj, Fridolin Grottker, Clara M. Reichardt, Jannik Alomo, Kerstin Borgmann, Benjamin Frey, Rainer Fietkau, Michael Rückert, Udo S. Gaipl
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-04-01
Серии:	Frontiers in Oncology
Предметы:	radiotherapy breast cancer radioresistance immune checkpoint molecules dendritic cells tumor cell death
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fonc.2023.981239/full
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