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Identification of Novel Alternative Transcripts of the Human ALKBH Gene Family and Investigation of Their Unique Expression Signatures in Cancer Cells

The human <i>ALKBH</i> gene family comprises nine Fe<sup>2+</sup>/α-ketoglutarate-dependent dioxygenases that catalyze the oxidative demethylation of DNA, RNA, and proteins, thereby influencing key cellular processes. Consequently, dysregulation of these enzymes has been implicated in various human...

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Principais autores: Konstantina Athanasopoulou, Vasiliki-Ioanna Michalopoulou, Panagiotis Tsiakanikas, Andreas Scorilas, Panagiotis G. Adamopoulos
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2026-02-01
coleção:Current Issues in Molecular Biology
Assuntos:
alternative splicing
demethylases
ALKBH
third-generation sequencing
direct RNA nanopore sequencing
qPCR
Acesso em linha:https://www.mdpi.com/1467-3045/48/3/251
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