Targeting Parthanatos in Ischemic Stroke
Parthanatos is a cell death signaling pathway in which excessive oxidative damage to DNA leads to over-activation of poly(ADP-ribose) polymerase (PARP). PARP then generates the formation of large poly(ADP-ribose) polymers that induce the release of apoptosis-inducing factor from the outer mitochondr...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2021-05-01
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| Serie: | Frontiers in Neurology |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/fneur.2021.662034/full |
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