KIR AA individuals possess strong inhibitory KIR alleles alongside HLA ligands that are protective against leukemia in the Chinese population

IntroductionThe killer-cell immunoglobulin-like receptor (KIR) gene cluster exhibits complicated diversity in haplotype content, copy-number variation (CNV), and allelic polymorphism. To date, 2,286 distinct KIR alleles have been released in the IPD-KIR Database. However, little is known about the i...

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Κύριοι συγγραφείς:	Zhihui Deng, Jianxin Zhen, Yunan Li, Shuang Liang, Manru Zhang, Siqi Cai, Renhui Jiang, Zhichao Yang, Qiong Yu, Jinyong Wang, Jie Liu
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2026-02-01
Σειρά:	Frontiers in Genetics
Θέματα:	ALL AML Chinese Southern Han HLA KIR leukemia
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fgene.2025.1745482/full
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