Glycyrrhizin as a potential disease-modifying therapy for epilepsy: insights into targeting pyroptosis to exert neuroprotective and anticonvulsant effects

BackgroundFor patients with epilepsy, antiseizure medication remains the primary treatment; however, it is ineffective in approximately 30% of cases. These patients experience progressive neuronal damage and poor outcomes. Therefore, there is an urgent need for disease-modifying therapy (DMT) that t...

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Principais autores:	Lei Wei, Sijie Ou, Youshi Meng, Lanfeng Sun, Lin Zhang, Yuling Lu, Yuan Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-01-01
Colecção:	Frontiers in Pharmacology
Assuntos:	epilepsy glycyrrhizin pyroptosis disease-modifying therapy neuroinflammation
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1530735/full
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