Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging
Type II nuclear receptors (T2NRs) require heterodimerization with a common partner, the retinoid X receptor (RXR), to bind cognate DNA recognition sites in chromatin. Based on previous biochemical and overexpression studies, binding of T2NRs to chromatin is proposed to be regulated by competition fo...
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| Format: | Artigo |
| Sprache: | Inglês |
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eLife Sciences Publications Ltd
2025-01-01
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| Schriftenreihe: | eLife |
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| Online-Zugang: | https://elifesciences.org/articles/92979 |
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