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Quantitative Measurement of GPCR Endocytosis via Pulse-Chase Covalent Labeling.

G protein-coupled receptors (GPCRs) play a critical role in many physiological systems and represent one of the largest families of signal-transducing receptors. The number of GPCRs at the cell surface regulates cellular responsiveness to their cognate ligands, and the number of GPCRs, in turn, is d...

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Autori principali: Hidetoshi Kumagai, Yuichi Ikeda, Yoshihiro Motozawa, Mitsuhiro Fujishiro, Tomohisa Okamura, Keishi Fujio, Hiroaki Okazaki, Seitaro Nomura, Norifumi Takeda, Mutsuo Harada, Haruhiro Toko, Eiki Takimoto, Hiroshi Akazawa, Hiroyuki Morita, Jun-ichi Suzuki, Tsutomu Yamazaki, Kazuhiko Yamamoto, Issei Komuro, Masashi Yanagisawa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2015-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4447269?pdf=render
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