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OPTIMIZATION OF CROSCARMELLOSE AND SODIUM STARCH GLYCOLATE ON ORALLY DISINTEGRATING METOCLOPRAMIDE HCL TABLETS

Dosage form of metoclopramide HCl which has high solubility but low permeability is Orally Disintegrating Tablet (ODT), because  can decrease first-pass-effect metabolism so that its bioavailability and effectiveness increase. Superdisintegrant is an excipient that has a major role in the formulati...

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Principais autores: Endang Diyah Ikasari, Intan Martha Cahyani, Deby Melinda Collusy
Format: Artigo
Sprog:Indonésio
Udgivet: Universitas Muhammadiyah Magelang 2022-12-01
Serier:Jurnal Farmasi Sains dan Praktis
Fag:
Croscarmellose
Metoclopramide HCl
Optimization
Orally disintegrating tablets
Sodium starch glycolate
Online adgang:http://journal.unimma.ac.id/index.php/pharmacy/article/view/4830
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