Mitochondrial Cytochrome c Oxidase Defects Alter Cellular Homeostasis of Transition Metals
The redox activity of cytochrome c oxidase (COX), the terminal oxidase of the mitochondrial respiratory chain (MRC), depends on the incorporation of iron and copper into its catalytic centers. Many mitochondrial proteins have specific roles for the synthesis and delivery of metal-containing cofactor...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Frontiers Media S.A.
2022-05-01
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| Schriftenreihe: | Frontiers in Cell and Developmental Biology |
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| Online-Zugang: | https://www.frontiersin.org/articles/10.3389/fcell.2022.892069/full |
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