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Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota

BackgroundUlcerative colitis (UC) is a chronic inflammatory bowel disease characterized by progressive loss of intestinal function, highlighting an urgent need for effective therapeutics. This study aimed to investigate the protective effects of Aurantii Fructus extract (AFE) on dextran sulfate sodi...

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Principais autores: JunBao Yu, WenYa Mei, JiaYuan Zhu, ZhiHui Wang, XiaoRong Liu, RiBao Zhou, XiangDan Liu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-10-01
Serier:Frontiers in Nutrition
Fag:
Aurantii Fructus
ulcerative colitis
intestinal flora
inflammation
oxidative stress
Online adgang:https://www.frontiersin.org/articles/10.3389/fnut.2025.1661040/full
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