Dysregulated autophagy, neural signaling pathways and gut-brain axis in a novel vestibular migraine-like rat model: implications for pathogenesis

Abstract Background Vestibular migraine (VM) pathophysiology remains incompletely understood, partly due to lacking validated animal models replicating its dual vestibular-nociceptive phenotype. This study aimed to establish a VM-like rat model and investigate associated mechanisms and gut microbiot...

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Autors principals:	Yanan Huang, Hongyan Li, Qihui Chen, Qijun Yu, Changman Zhang, Shanshan Shi, Yanxue Ren, Tingting Sun, Qingling Zhai, Jiarong Ban, Changchang Ying, Yonghui Pan
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-10-01
Col·lecció:	The Journal of Headache and Pain
Matèries:	Vestibular migraine Animal model Gut microbiota Metabolomics Autophagy CGRP
Accés en línia:	https://doi.org/10.1186/s10194-025-02170-5
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