<i>CYP2C</i>:<i>TG</i> Haplotype in Native Mexicans, Molecular Ancestry and Its Implications for <i>CYP2C19</i> Genotype–Phenotype Correlation

<b>Background:</b> Recent studies have associated the presence of the <i>CYP2C</i>:<i>TG</i> haplotype with increased metabolism of CYP2C19 substrates such as escitalopram and sertraline, suggesting a potential regulatory interaction between <i>CYP2C18</i> and <i>CYP2C19</i>. However, this associati...

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Detalhes bibliográficos

Principais autores:	Carla González de la Cruz, Nadine de Godoy Torso, Juan Antonio Villatoro-García, Carmen Mata-Martín, Fernanda Rodrigues-Soares, Carlos Galaviz-Hernández, Eva Peñas-Lledó, Martha Sosa-Macías, Adrián LLerena, RIBEF-IBEROFEN Consortium
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-12-01
coleção:	Pharmaceuticals
Assuntos:	<i>CYP2C</i>:<i>TG</i> haplotype CYP2C19 molecular ancestry native Mexican populations pharmacogenetics
Acesso em linha:	https://www.mdpi.com/1424-8247/19/1/6
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