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Autophagy Regulation Influences β-Amyloid Toxicity in Transgenic Caenorhabditis elegans

Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by the accumulation of amyloid-beta (Aβ) proteins in the form of plaques that cause a proteostasis imbalance in the brain. Several studies have identified autophagy deficits in both AD patients and AD animal models. H...

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Principais autores: Hongru Lin, Yehui Gao, Chen Zhang, Botian Ma, Mengchen Wu, Xianghuan Cui, Hongbing Wang
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2022-05-01
Serija:Frontiers in Aging Neuroscience
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Online dostop:https://www.frontiersin.org/articles/10.3389/fnagi.2022.885145/full
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