Melibiosamine, a novel oligosaccharide, suppresses mitogen-induced IL-2 production via inactivation of NFAT and NFκB in Jurkat cells

d-Glucosamine (GlcNH2) and several of its derivatives are known to possess immunosuppressive activities in various immune cell lines. The novel GlcNH2-containing oligosaccharide Galα1-6GlcNH2 (designated melibiosamine; MelNH2) is expected to be immunosuppressive also. In Jurkat cells (immortalized h...

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Detalhes bibliográficos

Principais autores:	Kazuki Fujita, Susumu Tanaka, Kyoichi Iizumi, Shuri Akiyama, Kaoru Uchida, Makoto Ogata, Daichi Aoki, Osamu Hosomi, Yuzuru Kubohara
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2019-09-01
coleção:	Biochemistry and Biophysics Reports
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S240558081930024X
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