Solid Dispersions Incorporated into PVP Films for the Controlled Release of Trans-Resveratrol: Development, Physicochemical and In Vitro Characterizations and In Vivo Cutaneous Anti-Inflammatory Evaluation

<i>Trans</i>-resveratrol can promote various dermatological effects. However, its high crystallinity decreases its solubility and bioavailability. Therefore, solid dispersions have been developed to promote its amorphization; even so, they present as powders, making cutaneous controlled drug deliver...

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Bibliografiske detaljer

Principais autores:	Bruno Vincenzo Fiod Riccio, André Luiz Carneiro Soares do Nascimento, Andréia Bagliotti Meneguin, Camila Fernanda Rodero, Kaio Pini Santos, Rafael Miguel Sábio, Sarah Raquel de Annunzio, Carla Raquel Fontana, Hernane da Silva Barud, Priscileila Colerato Ferrari, Marlus Chorilli
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2022-05-01
Serier:	Pharmaceutics
Fag:	amorphization anti-inflammatory activity antimicrobial effect crystallinity technological innovation skin permeation
Online adgang:	https://www.mdpi.com/1999-4923/14/6/1149
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