Cancer-associated fibroblast-derived stanniocalcin 1 promotes cholangiocarcinoma progression and lymph node metastasis

Cholangiocarcinoma (CCA) is a fibroblast-rich tumor. Lymph node metastasis (LNM) is the main prognostic risk factor for CCA. We determined that stanniocalcin 1 (STC1) is highly expressed in cancer-associated fibroblasts (CAFs) with LNM in CCA. However, the roles of CAFs and STC1 in CCA progression a...

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Главные авторы:	Jian Yan, Qinqin Liu, Gang Xiao, Jiajia Du, Caini Yang, Chaoqun Liu, Shusheng Lin, Zhenhua Bai, Chao Liu, Jingang Huang, Rui Zhang
Формат:	Artigo
Язык:	Inglês
Опубликовано:	KeAi Communications Co. Ltd. 2026-03-01
Серии:	Fundamental Research
Предметы:	Stanniocalcin 1 Lymph node metastasis Cholangiocarcinoma Integrin Cancer-associated fibroblasts
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2667325824000499
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