Hypothalamic kisspeptin alleviates myasthenia gravis by regulating Th1/Th17/Treg balance through Inhibition of NF-κB signaling pathway

Abstract Background Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular junctions. While neuroendocrine-immune system dysfunction plays a crucial role in the development of autoimmune diseases, its involvement in MG remains largely unexplored. Kisspeptin, a neuropeptide hormone...

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Detalhes bibliográficos

Principais autores:	Dan Lu, Linqi Liu, Wenjun Que, Rui Fan, Pingyang Ke, Jing Dong, Yaoqi Gan, Fei Xiao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-06-01
coleção:	Journal of Neuroinflammation
Assuntos:	Neuroendocrine-immune system Kisspeptin GPR54 NF-κB CD4+ T cell Myasthenia gravis
Acesso em linha:	https://doi.org/10.1186/s12974-025-03486-4
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