Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues

The DNA ligase of African swine fever virus is one of the most error-prone ligases identified to date, but underlying molecular details are lacking. Here, Chen et al. report four AsfvLIG:DNA structures and identify a unique N-terminal domain and four unique active site residues that are crucial for...

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Detalhes bibliográficos

Principais autores:	Yiqing Chen, Hehua Liu, Chun Yang, Yanqing Gao, Xiang Yu, Xi Chen, Ruixue Cui, Lina Zheng, Suhua Li, Xuhang Li, Jinbiao Ma, Zhen Huang, Jixi Li, Jianhua Gan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2019-01-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-019-08296-w
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