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Validation of a Cell Proliferation Assay to Assess the Potency of a Dialyzable Leukocyte Extract Intended for Batch Release

Transferon<sup>&#174;</sup> is a blood product with immunomodulatory properties constituted by a complex mixture of peptides obtained from a human dialyzable leukocyte extract (DLE). Due to its complex nature, it is necessary to demonstrate batch consistency in its biological activity. Potency is th...

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Автори: Gregorio Carballo-Uicab, José E. Linares-Trejo, Gabriela Mellado-Sánchez, Carlos A. López-Morales, Marco Velasco-Velázquez, Lenin Pavón, Sergio Estrada-Parra, Sonia Mayra Pérez-Tapia, Emilio Medina-Rivero
Формат: Artigo
Мова:Inglês
Опубліковано: MDPI AG 2019-09-01
Серія:Molecules
Предмети:
dialyzable leukocyte extract
Transferon<sup>®</sup>
complex mixture of peptides
quality specifications
biological potency
development and validation
Онлайн доступ:https://www.mdpi.com/1420-3049/24/19/3426
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