Be Aware of Aggregators in the Search for Potential Human ecto-5′-Nucleotidase Inhibitors
Promiscuous inhibition due to aggregate formation has been recognized as a major concern in drug discovery campaigns. Here, we report some aggregators identified in a virtual screening (VS) protocol to search for inhibitors of human ecto-5′-nucleotidase (ecto-5′-NT/CD73), a promising tar...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI AG
2018-07-01
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| Col·lecció: | Molecules |
| Matèries: | |
| Accés en línia: | http://www.mdpi.com/1420-3049/23/8/1876 |
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