Differential Effects of Oleic and Palmitic Acids on Lipid Droplet-Mitochondria Interaction in the Hepatic Cell Line HepG2

Fatty acid overload, either of the saturated palmitic acid (PA) or the unsaturated oleic acid (OA), causes triglyceride accumulation into specialized organelles termed lipid droplets (LD). However, only PA overload leads to liver damage mediated by mitochondrial dysfunction. Whether these divergent...

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Detalhes bibliográficos

Principais autores:	Andrea Eynaudi, Francisco Díaz-Castro, Juan Carlos Bórquez, Roberto Bravo-Sagua, Valentina Parra, Rodrigo Troncoso
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-11-01
coleção:	Frontiers in Nutrition
Assuntos:	lipid droplets mitochondria fatty acids hepatocytes oxygen consumption
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnut.2021.775382/full
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