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B cell receptor signaling and associated pathways in the pathogenesis of chronic lymphocytic leukemia

B cell antigen receptor (BCR) signaling is a key driver of growth and survival in both normal and malignant B cells. Several lines of evidence support an important pathogenic role of the BCR in chronic lymphocytic leukemia (CLL). The significant improvement of CLL patients’ survival with the use of...

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Autors principals: Vera K. Schmid, Elias Hobeika
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2024-02-01
Col·lecció:Frontiers in Oncology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fonc.2024.1339620/full
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