A systematic review and meta-analysis of noradrenaline compared to adrenaline in the management of septic shock

Background: Septic shock is associated with significant mortality. The International Surviving Sepsis Campaign guidelines recommend noradrenaline as first-line vasopressor, whilst South African guidelines recommend adrenaline. Clinical trials show similar efficacy but suggest safety advantages for n...

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Detalhes bibliográficos

Principais autores:	Trudy D Leong, Rephaim Mpofu, Sumaya Dadan, Karen Cohen, Halima Dawood, Tamara Kredo, Andy Parrish, Marc Blockman, P. Dean Gopalan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-09-01
coleção:	African Journal of Emergency Medicine
Assuntos:	Septic shock Adrenaline Noradrenaline Mortality Dysrhythmias Lactate
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211419X25000205
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