Neurotoxicity of immune checkpoint inhibitors: a retrospective pharmacovigilance study using FAERS database

BackgroundImmune checkpoint inhibitors (ICIs), an antitumor therapeutic strategy, have shown great potential for cancer treatment. With the widespread use of ICIs, immune-related adverse events (irAEs) have increased gradually. Neurotoxicity, as an irAE, has a low incidence rate, but high disability...

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Detalhes bibliográficos

Principais autores:	Lin Cao, Yanfei Wang, Peng Dai, Xia Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-03-01
coleção:	Frontiers in Immunology
Assuntos:	combination therapy CTLA-4 FAERS immune checkpoint inhibitors (ICIs) neurological adverse events PD-1/PD-L1
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1769013/full
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