Development of raft-forming liquid and chewable tablet formulations incorporating quercetin solid dispersions for treatment of gastric ulcers

Gastroretentive raft-forming formulations were developed in liquid and chewable tablet dosage forms to achieve prolonged delivery of quercetin in the stomach. The formulations contained a solid dispersion of quercetin and polyvinylpyrrolidone (PVP K 30) at a 1:10 w/w ratio to improve the solubility...

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Main Authors: Suputra Bunlung, Teerapat Nualnoi, Ousanee Issarachot, Ruedeekorn Wiwattanapatapee
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2021-10-01
Serier:Saudi Pharmaceutical Journal
Fag:
Quercetin
Gastric ulcers
Solid dispersions
Raft forming systems
Chewable tablets
Online adgang:http://www.sciencedirect.com/science/article/pii/S1319016421001523
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