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Retrospective cohort study comparing the risk of severe hepatotoxicity in hospitalized patients treated with echinocandins for invasive candidiasis in the presence of confounding by indication

Abstract Background To compare the risk of severe hepatotoxicity with anidulafungin versus caspofungin and micafungin in hospitalized adults. Methods This retrospective cohort study combined data from two large US- based hospital electronic medical record databases. Severe hepatotoxicity was a Grade...

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Autors principals: Francis Vekeman, Lisa Weiss, Jalal Aram, Raluca Ionescu-Ittu, Shahrzad Moosavi, Yongling Xiao, Wendy Y. Cheng, Rachel H. Bhak, Margaret Tawadrous, M. Rita Capparella, Philippe Montravers, Mei Sheng Duh
Format: Artigo
Idioma:Inglês
Publicat: BMC 2018-08-01
Col·lecció:BMC Infectious Diseases
Matèries:
Echinocandin
Anidulafungin
Caspofungin
Micafungin
Severe hepatotoxicity
Accés en línia:http://link.springer.com/article/10.1186/s12879-018-3333-0
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