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Chronic Exposure to Nitric Oxide Induces P53 Mutations and Malignant-like Features in Human Breast Epithelial Cells

The small endogenous signaling molecule nitric oxide (NO) has been linked with chronic inflammation and cancer. The effects of NO are both concentration and temporally dependent; under some conditions, NO protects against damage caused by reactive oxygen species and activates P53 signaling. During c...

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Principais autores: Robert Y. S. Cheng, Sandra Burkett, Stefan Ambs, Terry Moody, David A. Wink, Lisa A. Ridnour
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-02-01
coleção:Biomolecules
Assuntos:
nitric oxide
TP53
mutation
breast cancer
Acesso em linha:https://www.mdpi.com/2218-273X/13/2/311
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