Unraveling the Interplay of KRAS, NRAS, BRAF, and Micro-Satellite Instability in Non-Metastatic Colon Cancer: A Systematic Review

Microsatellite Instability (MSI-H) occurs in approximately 15% of non-metastatic colon cancers, influencing patient outcomes positively compared to microsatellite stable (MSS) cancers. This systematic review focuses on the prognostic significance of KRAS, NRAS, and BRAF mutations within MSI-H colon...

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Autori principali:	Elena Orlandi, Mario Giuffrida, Serena Trubini, Enrico Luzietti, Massimo Ambroggi, Elisa Anselmi, Patrizio Capelli, Andrea Romboli
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-05-01
Serie:	Diagnostics
Soggetti:	colonic neoplasms microsatellite instability mutation neoplasm staging prognosis proto-oncogene proteins B-raf proto-oncogene proteins p21(ras)
Accesso online:	https://www.mdpi.com/2075-4418/14/10/1001
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