Engineered Biomimetic Fibrillar Fibronectin Matrices Regulate Cell Adhesion Initiation, Migration, and Proliferation via α5β1 Integrin and Syndecan‐4 Crosstalk

Abstract Cells regulate adhesion to the fibrillar extracellular matrix (ECM) of which fibronectin is an essential component. However, most studies characterize cell adhesion to globular fibronectin substrates at time scales long after cells polarize and migrate. To overcome this limitation, a simple...

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Autors principals:	Seungkuk Ahn, Upnishad Sharma, Krishna Chaitanya Kasuba, Nico Strohmeyer, Daniel J. Müller
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2023-08-01
Col·lecció:	Advanced Science
Matèries:	3D fibrillar fibronectin adhesion initiation extracellular matrix integrin spatiotemporal cell dynamics syndecan
Accés en línia:	https://doi.org/10.1002/advs.202300812
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