Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma

Summary: Esophageal adenocarcinoma (EAC) is a highly lethal cancer of the upper gastrointestinal tract with rising incidence in western populations. To decipher EAC disease progression and therapeutic response, we perform multiomic analyses of a cohort of primary and metastatic EAC tumors, incorpora...

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Detalhes bibliográficos

Principais autores:	Josephine Yates, Camille Mathey-Andrews, Jihye Park, Amanda Garza, Andréanne Gagné, Samantha Hoffman, Kevin Bi, Breanna Titchen, Connor Hennessey, Joshua Remland, Matthew Carnes, Erin Shannon, Sabrina Camp, Siddhi Balamurali, Shweta Kiran Cavale, Zhixin Li, Akhouri Kishore Raghawan, Agnieszka Kraft, Genevieve Boland, Andrew J. Aguirre, Nilay S. Sethi, Valentina Boeva, Eliezer M. Van Allen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-06-01
Colecção:	Cell Reports Medicine
Assuntos:	esophageal adenocarcinoma gastrointestinal cancer computational biology epigenetics transcriptomics spatial transcriptomics
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2666379125002617
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