Diarylpentanoid (1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadiene-3-one) (MS13) Exhibits Anti-proliferative, Apoptosis Induction and Anti-migration Properties on Androgen-independent Human Prostate Cancer by Targeting Cell Cycle–Apoptosis and PI3K Signalling Pathways

Diarylpentanoids exhibit a high degree of anti-cancer activity and stability in vitro over curcumin in prostate cancer cells. Hence, this study aims to investigate the effects of a diarylpentanoid, 1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadiene-3-one (MS13) on cytotoxicity, anti-proliferative, ap...

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Hauptverfasser:	Nurul Azwa Abd. Wahab, Faridah Abas, Iekhsan Othman, Rakesh Naidu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-07-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	diarylpentanoid androgen-independent prostate cancer anti-cancer cell cycle apoptosis anti-migration
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphar.2021.707335/full
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