QR-Code

Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope

The heavy chain IGHV1-69 germline gene exhibits a high level of polymorphism and shows biased use in protective antibody (Ab) responses to infections and vaccines. It is also highly expressed in several B cell malignancies and autoimmune diseases. G6 is an anti-idiotypic monoclonal Ab that selective...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Yuval Avnir, Kristina L. Prachanronarong, Zhen Zhang, Shurong Hou, Eric C. Peterson, Jianhua Sui, Hatem Zayed, Vinodh B. Kurella, Andrew T. McGuire, Leonidas Stamatatos, Brendan J. Hilbert, Markus-Frederik Bohn, Timothy F. Kowalik, Jeffrey D. Jensen, Robert W. Finberg, Jennifer P. Wang, Margaret Goodall, Roy Jefferis, Quan Zhu, Nese Kurt Yilmaz, Celia A. Schiffer, Wayne A. Marasco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017-12-01
Schriftenreihe:Cell Reports
Schlagworte:
influenza
anti-idiotypic antibody
cross-reactive idiotype
chronic lymphocytic leukemia
VH germline genes
IGHV polymorphism
anti-influenza antibodies
immunoglobulin germline genes
crystal structure
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2211124717317084
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge