Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS

Local protein synthesis in neuronal axons plays an important role in essential spatiotemporal signaling processes; however, the molecular basis for the post-transcriptional regulation controlling this process in axons is still not fully understood. Here we studied the axonal mechanisms underlying th...

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Autors principals:	Noga Gershoni-Emek, Topaz Altman, Ariel Ionescu, Christopher J. Costa, Tal Gradus-Pery, Dianna E. Willis, Eran Perlson
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2018-09-01
Col·lecció:	Frontiers in Molecular Neuroscience
Matèries:	axonal transport microRNA mitochondria RISC ALS Dicer
Accés en línia:	https://www.frontiersin.org/article/10.3389/fnmol.2018.00311/full
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