CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection

Host response to RNA virus infection is sensed by RNA sensors such as RIG-I, which induces MAVS-mediated NF-κB and IRF3 activation to promote inflammatory and antiviral responses, respectively. Here, we have found that CARMA3, a scaffold protein previously shown to mediate NF-κB activation induced b...

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Principais autores:	Changying Jiang, Zhicheng Zhou, Yanping Quan, Shilei Zhang, Tingting Wang, Xueqiang Zhao, Clayton Morrison, Mark T. Heise, Wenqian He, Matthew S. Miller, Xin Lin
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2016-03-01
Series:	Cell Reports
Assuntos:	CARMA3 CARD10 IRF3 NF-κB viral infection
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2211124716301346
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