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Predicting the methylation status of CpG islands from read distribution biases

Abstract DNA methylation is an important epigenetic mark that plays a major role in transcriptional regulation, development and genome integrity. There are state-of-the-art methods, such as whole-genome bisulfite sequencing or long-read sequencing, which allow accurate detection of DNA methylation a...

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Autori principali: Eldar T. Abdullaev, Dinesh A. Haridoss, Peter F. Arndt
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-10-01
Serie:BMC Genomics
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Accesso online:https://doi.org/10.1186/s12864-025-12257-7
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