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Functional consequence of myeloid ferritin heavy chain on acute and chronic effects of rhabdomyolysis-induced kidney injury

Acute kidney injury (AKI) is a serious complication of rhabdomyolysis that significantly impacts survival. Myoglobin released from the damaged muscle accumulates in the kidney, causing heme iron-mediated oxidative stress, tubular cell death, and inflammation. In response to injury, myeloid cells, sp...

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Principais autores: Kayla R. McCullough, Juheb Akhter, Mauhaun J. Taheri, Amie Traylor, Anna A. Zmijewska, Vivek Verma, Matthew C. Hudson, Abhishek Sachdeva, Elise N. Erman, Kyle H. Moore, James F. George, Subhashini Bolisetty
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-09-01
coleção:Frontiers in Medicine
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmed.2022.894521/full
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