An interdependent network of functional enhancers regulates transcription and EZH2 loading at the INK4a/ARF locus
Summary: The INK4a/ARF locus encodes important cell-cycle regulators p14ARF, p15INK4b, and p16INK4a. The neighboring gene desert to this locus is the most reproducible GWAS hotspot that harbors one of the densest enhancer clusters in the genome. However, how multiple enhancers that overlap with GWAS...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2021-03-01
|
| Seri Bilgileri: | Cell Reports |
| Konular: | |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2211124721002126 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|