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Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy

Abstract Background Gallbladder cancer is the most common biliary tract malignancy and not sensitive to chemotherapy. Autophagy is an important factor prolonging the survival of cancer cells under chemotherapeutic stress. We aimed to investigate the role of long non-coding RNAs (lncRNAs) in autophag...

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Principais autores: Qiang Cai, Shouhua Wang, Longyang Jin, Mingzhe Weng, Di Zhou, Jiandong Wang, Zhaohui Tang, Zhiwei Quan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-04-01
coleção:Molecular Cancer
Assuntos:
lncRNA GBCDRlnc1
Gallbladder cancer
Chemoresistance
Autophagy
PGK1
Acesso em linha:http://link.springer.com/article/10.1186/s12943-019-1016-0
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