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<i>HES6</i> knockdown in human hematopoietic precursor cells reduces their <i>in vivo</i> engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells

Hematopoiesis is driven by molecular mechanisms that induce differentiation and proliferation of hematopoietic stem cells and their progeny. This involves the activity of various transcription factors, such as members of the Hairy/Enhancer of Split (HES) family, and important roles for both HES1 an...

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Bibliografiske detaljer
Principais autores: Tamara De Vos, Nicole Oatman, Lena Boehme, Tom Putteman, Imke Velghe, Yana Van Droogenbroeck, Stijn De Munter, Michaela Cesnekova, Filip Van Nieuwerburgh, Bart Vandekerckhove, Jan Philippe, Tom Taghon
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2024-04-01
Serier:Haematologica
Online adgang:https://haematologica.org/article/view/11534
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