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Identification and validation of stemness-based and ferroptosis-related molecular clusters in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with an extremely poor prognosis. Cancer stem cells (CSCs) are considered to be responsible for the poor survival, recurrence and therapy resistance of PDAC. Ferroptosis plays a crucial role in the sustain and survival of CSCs. He...

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Principais autores: Shiye Ruan, Hailiang Wang, Zhongyan Zhang, Qian Yan, Yubin Chen, Jinwei Cui, Shanzhou Huang, Qi Zhou, Chuanzhao Zhang, Baohua Hou
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-03-01
Serier:Translational Oncology
Fag:
Pancreatic ductal adenocarcinoma
Cancer stem cells
Ferroptosis
ARNTL2
CD133
Online adgang:http://www.sciencedirect.com/science/article/pii/S1936523324000032
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