Impact of Rh five-antigen–matched transfusion on alloimmunization and clinical outcomes in patients requiring repeated red blood cell transfusions: a prospective randomized controlled study

BackgroundRed blood cell (RBC) alloimmunization remains a significant challenge in patients requiring repeated transfusions, complicating transfusion procedures and increasing healthcare resource utilization. While extended Rh antigen matching has been proposed to mitigate alloimmunization, prospect...

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Principais autores:	Xiaolu Xie, Ye Qin, Hanke Wang, Jun Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-04-01
coleção:	Frontiers in Medicine
Assuntos:	randomized controlled study red blood cell alloimmunization repeated red blood cell transfusion Rh antigen matching transfusion management
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1795865/full
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