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Is the proximal tubule the focus of tubulointerstitial fibrosis?

Tubulointerstitial fibrosis (TIF), a common end result of almost all progressive chronic kidney diseases (CKD), is also the best predictor of kidney survival. Almost all cells in the kidney are involved in the progression of TIF. Myofibroblasts, the primary producers of extracellular matrix, have pr...

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Principais autores: Zhi Peng, Hui Wang, Jiaoyun Zheng, Jie Wang, Yang Xiang, Chi Liu, Ming Ji, Huijun Liu, Lang Pan, Xiaoqun Qin, Xiangping Qu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2023-02-01
coleção:Heliyon
Assuntos:
Proximal tubule
Tubulointerstitial fibrosis
Extracellular matrix
Chronic kidney disease
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2405844023007156
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