Multivariate stochastic modeling for transcriptional dynamics with cell-specific latent time using SDEvelo

Abstract Recently, RNA velocity has driven a paradigmatic change in single-cell RNA sequencing (scRNA-seq) studies, allowing the reconstruction and prediction of directed trajectories in cell differentiation and state transitions. Most existing methods of dynamic modeling use ordinary differential e...

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Podrobná bibliografie

Hlavní autoři:	Xu Liao, Lican Kang, Yihao Peng, Xiaoran Chai, Peng Xie, Chengqi Lin, Hongkai Ji, Yuling Jiao, Jin Liu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-12-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-024-55146-5
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