Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity
Engineering antibodies to elicit antibody‐dependent cell‐mediated cytotoxicity (ADCC) can be used to eliminate target cells. Here, we described how single domain VHH arms on a bispecific antibody (BsAb) format can be engineered to modulate cell binding and ADCC activity. The BsAbs, comprising two an...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wiley
2026-05-01
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| Serie: | FEBS Open Bio |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1002/2211-5463.70166 |
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