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Cellular-level analyses of SCN5A mutations in left ventricular noncompaction cardiomyopathy suggest electrophysiological mechanisms for ventricular tachycardia

Left ventricular noncompaction cardiomyopathy (LVNC) is a cardiovascular disease characterized by arrhythmia and heart failure. In this study, LVNC myocardial samples were collected from patients who underwent heart transplantation and were analyzed using exome sequencing. Approximately half of the...

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Principais autores: Yanfen Li, Shenghua Liu, Jian Huang, Yuanyuan Xie, Aijie Hou, Yingjie Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-03-01
coleção:Biochemistry and Biophysics Reports
Assuntos:
SCN5A
Variant
LVNC
Arrhythmia
Tachycardia
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2405580824000177
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