Glutamate spillover in C. elegans triggers repetitive behavior through presynaptic activation of MGL-2/mGluR5

Katz and colleagues examine glutamate spillover effects on C. elegans behaviour. They show that impaired synaptic glutamate clearance in glial glutamate transporter mutants, causes presynaptic mgl-2/mGluR5 activation, generating postsynaptic neural activity oscillations driving repetitive behaviour.

Detalhes bibliográficos

Principais autores:	Menachem Katz, Francis Corson, Wolfgang Keil, Anupriya Singhal, Andrea Bae, Yun Lu, Yupu Liang, Shai Shaham
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2019-04-01
Colecção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-019-09581-4
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