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Cholecystokinin Receptor-Targeted Polyplex Nanoparticle Inhibits Growth and Metastasis of Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) remains the most aggressive malignancy with the lowest 5-year survival rate of all cancers in part owing to the lack of tumor-specific therapy and the rapid metastatic nature of this cancer. The gastrointestinal peptide gastrin is a trophic peptide that stimul...

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Principais autores: Julian Burks, Sandeep Nadella, Abdullah Mahmud, Charoen Mankongpaisarnrung, Juan Wang, Jong-In Hahm, Robin D. Tucker, Narayan Shivapurkar, Stephan T. Stern, Jill P. Smith
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018-01-01
Serier:Cellular and Molecular Gastroenterology and Hepatology
Fag:
CCK Receptor
Gene Therapy
Gastrin
Nanotechnology
Orthotopic
Online adgang:http://www.sciencedirect.com/science/article/pii/S2352345X1830050X
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