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Small Extracellular Vesicles from adipose derived stromal cells significantly attenuate in vitro the NF-κB dependent inflammatory/catabolic environment of osteoarthritis

Abstract The therapeutic ability of Mesenchymal Stem/Stromal Cells to address osteoarthritis (OA) is mainly related to the secretion of biologically active factors, which can be found within their secreted Extracellular Vesicles including small Extracellular Vesicles (sEV). Aim of this study was to...

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Detalhes bibliográficos
Principais autores: Carola Cavallo, Giulia Merli, Rosa Maria Borzì, Nicoletta Zini, Stefania D’Adamo, Michele Guescini, Brunella Grigolo, Alessandro Di Martino, Spartaco Santi, Giuseppe Filardo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2021-01-01
coleção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-020-80032-7
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