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Cardiomyocyte Marker Expression in Mouse Embryonic Fibroblasts by Cell-Free Cardiomyocyte Extract and Epigenetic Manipulation

Background: The regenerative capacity of the mammalian heart is quite limited. Recent reports have focused on reprogramming mesenchymal stem cells into cardiomyocytes. We investigated whether fibroblasts could transdifferentiate into myocardium. Methods: Mouse embryonic fibroblasts were treated wit...

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Principais autores: Tahereh Talaei-Khozani, Fatemeh Heidari, Tahereh Esmaeilpour, Zahra Vojdani, Zohrah Mostafavi-Pour, Leili Rohani
Format: Artigo
Sprog:Inglês
Udgivet: Shiraz University of Medical Sciences 2014-03-01
Serier:Iranian Journal of Medical Sciences
Fag:
Cardiomyocytes
Cell transdifferentiation
Histone deacetylase inhibitors
Fibroblast
Online adgang:http://ijms.sums.ac.ir/index.php/IJMS/article/view/645
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